Peripheral Artery Disease (PAD)

With this condition, your limbs -- typically your legs -- don’t get enough blood. It usually happens because your arteries have narrowed. Your legs may feel weak or numb or cramp when you walk. They might feel cold and be an odd color. Some people can manage PAD with habit changes, like quitting smoking. If that doesn’t work, your doctor might give you medicine to treat the problem or help with pain. But some people need surgery.

Deep Vein Thrombosis (DVT)

This is a blood clot in a vein, usually in your thigh or lower leg. It doesn’t always cause symptoms, but you might have pain, swelling in your leg, and it might be warm and red. Call your doctor right away if you notice any of these. DVT can lead to a serious condition called a pulmonary embolism -- when the clot breaks off and goes to your lungs. Your doctor can give you medicine to keep clots from forming, growing, or breaking off.

Peripheral Neuropathy

This happens when there’s damage to the nerves in your body that relay messages to and from your brain. The most common cause is diabetes, but other health conditions, medicines, injuries, or infections can cause it. If it affects the nerves in your legs, they might feel prickly or tingly, or they might be numb or weak. Your doctor will treat the condition that’s causing it and give you medicine for pain if you need it.

Electrolyte Imbalance

Electrolytes are minerals like sodium, potassium, and calcium that help your muscles work the way they should. You lose some through sweat when you exercise, and if you lose too much, your legs can cramp or feel weak or numb. It can happen when you get some medical treatments, like chemotherapy, too. Sports drinks with electrolytes -- or water along with foods that have those minerals -- can help. See your doctor if you cramp up often.

Spinal Stenosis

This condition happens when the spaces within the bones in your spine get narrow. That puts pressure on the nerves in the area and can cause pain, tingling, numbness, or weakness in your legs. You also might have trouble with balance. See your doctor right away if you have any of these symptoms. Medication can ease the pain, and physical therapy can help, too. If these don’t work, you might need surgery.